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Mantle cell lymphoma

3 associated genes
7 signs/symptoms

PROTEIN INTERACTIONS: 1

Familial hypospadias

4 OMIM references -
2 associated genes
1 sign/symptom

Mantle cell lymphoma

Familial hypospadias

ATM	(UniProt - OMIM)		AR	(UniProt - OMIM)
CCND1	(UniProt - OMIM)		MAMLD1	(UniProt - OMIM)
IGH	(UniProt)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	CCND1	(0.9)	AR

Citations in the biomedical literature:

Mantle cell lymphoma		Familial hypospadias
	Synonym(s): - LCM - MCL - Mantle zone lymphoma		Synonym(s): (no synonyms)

	Classification (Orphanet): - Rare hematologic disease - Rare oncologic disease		Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare genetic disease - Rare urogenital disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: adulthood Average age of death: adult Type of inheritance: multigenic/multifactorial		Epidemiological data: Class of prevalence: unknown Average age onset: neonatal/infancy Average age of death: normal Type of inheritance: autosomal dominant

	External references: No OMIM references 1 MeSH reference: D020522		External references: 4 OMIM references - No MeSH references

Mantle cell lymphoma		Familial hypospadias
	Very frequent - Hematologic / blood / lymphatic cancer - Lymphadenopathy / polyadenopathies Frequent - Anorexia - Asthenia / fatigue / weakness - Bone marrow / medullar infiltration - Splenomegaly - Weight loss / loss of appetite / break in weight curve / general health alteration		Very frequent - Hypospadias / epispadias / bent penis